Mavrilas Dimosthenis
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Mavrilas Dimosthenis
Academic position: Associate Professor (Retired Faculty Member)
Biographic Notes
Born in Amaliada Hleias/GR, 1953. Degree of Physics (1980), PhD (1991) Dept. Mechanical Engineering, University of Patras. – (1981 – 1993) Research Assoc. Department of Mechanical Engineering, University of Patras. – (1993 – 2004) Lecturer, Department of Mechanical Engineering, University of Patras. – (2004-2013) Assistant Professor, (2013-Today) Associate Professor, Department of Mechanical Engineering, University of Patras. Member of Laboratory of Biomechanics & Biomedical Engineering. Ressearch interests in Biomechanics, Biomaterials, Artificial Organs, Tissue Engineering.
He was Vice-President of the Hellenic Society of Biomechanics (2006-2008) – President (2008-2010), executive board member (2014-2016). He is a member of the Hellenic Society of Biomechanics (HSB), Hellenic society of Biomaterials, European Society for Artificial Organs (ESAO) and European Society of Biomechanics (ESB).
Research Projects
- “Resorbable continuous fibber reinforced polymers for osteosynthesis” (1993 – 1996) ) “Brite/Euram” (EC).
- “New techniques of fixation of bioprosthetic heart valves. Correlation with calcification” (1995 – 1996) (Project leader) “Bilateral co-operation between Greek – Romania” (GSRT).
- “Calcification of bioprosthetic implants in vivo and in vitro. Mechanisms of initiation, enhancement and elimination and protection” (1996-1998) (Project leader) “PENED 95” (GSRT).
- “Study of structure – mechanical function relation of soft tissues. Correlation with calcification mechanisms” (2000 – 2003) (Project leader) “K. Karatheodoris” (Un. Patras, Res. Comitee).
- “Study of the role of mechanical stress in calcification of biological heart valves”. (2004-2005) (Project leader) “Bilateral co-operation between Greek – Germany” (ΙΚΥ-DAAD).
- COST 537Core Laboratories for the Improvement of Medical Devices in Clinical Practice from the Failure of the Explanted Prostheses Analysis (FEPA) (2005) (EC).
- “Study ofchanges in structural integrity of naturally oriented biomaterials and its correlation with associated mechanical behaviour and biocompatibility” (2006 – 2009) (Project leader) “K. Karatheodoris” (Un. Patras, Res. Comitee).
- “Study of biomechanics and biocompatibility of tissue-engineering biomaterials”. (2010-2011) (Project leader) “Bilateral co-operation between Greek – Germany” (ΙΚΥ-DAAD).
«Towards Tissue Engineering Solutions for Cardiovascular Surgery (TECAS) ». (2013-2016) (Project leader of group UPatras, FP7-PEOPLE-2012-Marie Curie-MultiITN).
Recent Publications
- Fidalgo, C., Iop, L., Sciro, M., Harder, M., Mavrilas, D., Korossis, S., Bagno, A., Palù, G., Aguiari, P., Gerosa, G.,: Sterilization Method for Decellularized Xenogeneic Cardiovascular Scaffolds, Acta Biomaterialia 67:282–294 (2018), https://doi.org/10.1016/j.actbio.2017.11.035
- F. Badria, P. Koutsoukos, C. D’Alessandro, S. Korossis, D. Mavrilas.: Anticalcification potential of heparin on hydroxyapatite seeds using a constant composition in vitro model, Journal of Crystal Growth 498;399–404 (2018), https://doi.org/10.1016/j.jcrysgro.2018.07.011.
- Markatos DN, Sarakinis A, Mavrilas D.: Tuning Fiber Alignment to Achieve Mechanical Anisotropy on Polymeric Electrospun Scaffolds for Cardiovascular Tissue Engineering. J Material Sci Eng 7: 466. doi: 10.4172/2169-0022.1000466
- A. Badria, P. Koutsoukos, S. Korossis, D. Mavrilas.: The effect of heparin hydrogel embedding on glutaraldehyde fixed bovine pericardial tissues: Mechanical behavior and anticalcification potential. Journal of Materials Science: Materials in Medicine; 29:175 (2018). https://doi.org/10.1007/s10856-018-6184-8
- Pagoulatou E., Mavrilas D.: Assessment of endothelial cell proliferation and adhesion strength on decellularized bovine pericardial scaffolds for tissue engineering. Curr Res Regen Med Tissue Eng: CRRT-104. (2018)
- A. Mitropoulou, D. Markatos, S. Antimisiari, D. Mavrilas.: A novel design of PVA electrospun nanofibrous scaffold incorporating liposomes as drug delivery carriers for tissue engineering. Annals of Biomedical Technology & Engineering (Ann Biomed Technol Eng.;1(1): 1003. ( 2018).
Google Scholar: Μαυρίλας Δημοσθένης
Scopus: Μαυρίλας Δημοσθένης
Contact hours: Tuesday-Thursday:00-13:00
Research Fields
He has 38 years of research experience in the area of biomaterials, biomechanics and artificial organs.
His research activities include coordination or participation of funded research projects at related areas. Among others, his research activities involved the development of new methods for fixation of bioprosthetic heart valves, testing of mechanical and fluid-mechanical performance of prosthetic heart valves and blood vessels, development of bioresorbable biomaterials for osteosynthesis, study of calcification and atheromatic plaque formation of implantable biomaterials in vivo and in vitro, cardiovascular tissue engineering scaffolds from natural soft biomaterials, as well design & production of electrospuned polymeric micro-nano fibrous structured scaffolds for tissue engineering applications.
Courses
Postgraduate Study Program
- Biomaterials for Tissue Engineering
- Biomechanical Analysis and Design of Artificial Organs
Undergraduate Study Program
There are no available courses!